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Guanylate-Binding Proteins Are Critical for Effective Control of Francisella tularensis Strains in a Mouse Co-Culture System of Adaptive Immunity

Francisella tularensis is a Select Agent that causes the severe disease tularemia in humans and many animal species. The bacterium demonstrates rapid intracellular replication, however, macrophages can control its replication if primed and activation with IFN-γ is known to be essential, although alo...

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Detalles Bibliográficos
Autores principales: Mohammadi, Nasibeh, Lindgren, Helena, Golovliov, Igor, Eneslätt, Kjell, Yamamoto, Masahiro, Martin, Amandine, Henry, Thomas, Sjöstedt, Anders
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7758253/
https://www.ncbi.nlm.nih.gov/pubmed/33363054
http://dx.doi.org/10.3389/fcimb.2020.594063