Modeling Rett Syndrome With Human Patient-Specific Forebrain Organoids

Engineering brain organoids from human induced pluripotent stem cells (hiPSCs) is a powerful tool for modeling brain development and neurological disorders. Rett syndrome (RTT), a rare neurodevelopmental disorder, can greatly benefit from this technology, since it affects multiple neuronal subtypes...

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Detalles Bibliográficos
Autores principales: Gomes, Ana Rita, Fernandes, Tiago G., Vaz, Sandra H., Silva, Teresa P., Bekman, Evguenia P., Xapelli, Sara, Duarte, Sofia, Ghazvini, Mehrnaz, Gribnau, Joost, Muotri, Alysson R., Trujillo, Cleber A., Sebastião, Ana M., Cabral, Joaquim M. S., Diogo, Maria Margarida
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2020
Materias:
Cell and Developmental Biology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7758289/
https://www.ncbi.nlm.nih.gov/pubmed/33363173
http://dx.doi.org/10.3389/fcell.2020.610427

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7758289/
https://www.ncbi.nlm.nih.gov/pubmed/33363173
http://dx.doi.org/10.3389/fcell.2020.610427

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