Mitochondrial Fission and Mitophagy Coordinately Restrict High Glucose Toxicity in Cardiomyocytes

Hyperglycemia-induced mitochondrial dysfunction plays a key role in the pathogenesis of diabetic cardiomyopathy. Injured mitochondrial segments are separated by mitochondrial fission and eliminated by autophagic sequestration and subsequent degradation in the lysosome, a process termed mitophagy. Ho...

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Detalles Bibliográficos
Autores principales: Kobayashi, Satoru, Zhao, Fengyi, Zhang, Ziying, Kobayashi, Tamayo, Huang, Yuan, Shi, Bingyin, Wu, Weihua, Liang, Qiangrong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2020
Materias:
Physiology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7758327/
https://www.ncbi.nlm.nih.gov/pubmed/33362579
http://dx.doi.org/10.3389/fphys.2020.604069

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7758327/
https://www.ncbi.nlm.nih.gov/pubmed/33362579
http://dx.doi.org/10.3389/fphys.2020.604069

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