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CDK 4/6 inhibitors mired in uncertainty in HR positive and HER2 negative early breast cancer
Cell-cycle abnormalities are common in estrogen receptor- and/or progesterone receptor-positive, and HER2-non-overexpressing (HR+/HER2-) breast cancer, and have long been considered potential therapeutic targets. Cyclin-dependent kinase (CDK) 4/6 inhibitors have dramatically changed the therapeutic...
Autores principales: | , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7758367/ https://www.ncbi.nlm.nih.gov/pubmed/33352521 http://dx.doi.org/10.1016/j.breast.2020.12.006 |