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Design, Synthesis, and Antitumor Activities Study of Stapled A4K14-Citropin 1.1 Peptides

A4K14-citropin 1.1 is a structurally optimized derivative derived from amphibians' skin secreta peptide Citropin, which exhibits broad biological activities. However, the application of A4K14-citropin 1.1 as a cancer therapeutic is restricted by its structural flexibility. In this study, a seri...

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Detalles Bibliográficos
Autores principales: Wang, Nan, Xie, Gang, Liu, Chao, Cong, Wei, He, Shipeng, Li, Yinghua, Fan, Li, Hu, Hong-Gang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7758422/
https://www.ncbi.nlm.nih.gov/pubmed/33363118
http://dx.doi.org/10.3389/fchem.2020.616147