Adjunct Therapy With Glycyrrhiza Glabra Rapidly Improves Outcome in Depression—A Pilot Study to Support 11-Beta-Hydroxysteroid Dehydrogenase Type 2 Inhibition as a New Target

Mineralocorticoid-receptor (MR) dysfunction as expressed by low systolic blood pressure and a high salivary aldosterone/cortisol ratio predicts less favorable antidepressant treatment outcome. Inhibition of peripheral 11-beta-hydroxysteroid-dehydrogenase type 2 (11betaHSD2) reverses these markers. W...

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Detalles Bibliográficos
Autores principales: Murck, Harald, Lehr, Lisa, Hahn, Johannes, Braunisch, Matthias C., Jezova, Daniela, Zavorotnyy, Maxim
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2020
Materias:
Psychiatry
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7758437/
https://www.ncbi.nlm.nih.gov/pubmed/33362613
http://dx.doi.org/10.3389/fpsyt.2020.605949

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7758437/
https://www.ncbi.nlm.nih.gov/pubmed/33362613
http://dx.doi.org/10.3389/fpsyt.2020.605949

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