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Treatment of Rare Inflammatory Kidney Diseases: Drugs Targeting the Terminal Complement Pathway
The complement system comprises the frontline of the innate immune system. Triggered by pathogenic surface patterns in different pathways, the cascade concludes with the formation of a membrane attack complex (MAC; complement components C5b to C9) and C5a, a potent anaphylatoxin that elicits various...
Autores principales: | , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7758461/ https://www.ncbi.nlm.nih.gov/pubmed/33362783 http://dx.doi.org/10.3389/fimmu.2020.599417 |