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Unorthodox Transcriptional Mechanisms of Lipid-Sensing Nuclear Receptors in Macrophages: Are We Opening a New Chapter?

Work over the past 30 years has shown that lipid-activated nuclear receptors form a bridge between metabolism and immunity integrating metabolic and inflammatory signaling in innate immune cells. Ligand-induced direct transcriptional activation and protein-protein interaction-based transrepression w...

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Detalles Bibliográficos
Autores principales: Czimmerer, Zsolt, Halasz, Laszlo, Nagy, Laszlo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7758493/
https://www.ncbi.nlm.nih.gov/pubmed/33362723
http://dx.doi.org/10.3389/fendo.2020.609099