Cargando…
Unorthodox Transcriptional Mechanisms of Lipid-Sensing Nuclear Receptors in Macrophages: Are We Opening a New Chapter?
Work over the past 30 years has shown that lipid-activated nuclear receptors form a bridge between metabolism and immunity integrating metabolic and inflammatory signaling in innate immune cells. Ligand-induced direct transcriptional activation and protein-protein interaction-based transrepression w...
Autores principales: | Czimmerer, Zsolt, Halasz, Laszlo, Nagy, Laszlo |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2020
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7758493/ https://www.ncbi.nlm.nih.gov/pubmed/33362723 http://dx.doi.org/10.3389/fendo.2020.609099 |
Ejemplares similares
-
PPARs are a unique set of fatty acid regulated transcription factors controlling both lipid metabolism and inflammation()
por: Varga, Tamas, et al.
Publicado: (2011) -
Transcriptional repression shapes the identity and function of tissue macrophages
por: Bene, Krisztian, et al.
Publicado: (2021) -
The transcriptional control of the VEGFA-VEGFR1 (FLT1) axis in alternatively polarized murine and human macrophages
por: Domokos, Apolka, et al.
Publicado: (2023) -
The transcription factor EGR2 is the molecular linchpin connecting STAT6 activation to the late, stable epigenomic program of alternative macrophage polarization
por: Daniel, Bence, et al.
Publicado: (2020) -
Unorthodox epidemiology
por: Tyrrell, D. A. J.
Publicado: (1979)