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Spatiotemporal Up-Regulation of Mu Opioid Receptor 1 in Striatum of Mouse Model of Huntington’s Disease Differentially Affecting Caudal and Striosomal Regions

The striatum of humans and other mammals is divided into macroscopic compartments made up of a labyrinthine striosome compartment embedded in a much larger surrounding matrix compartment. Anatomical and snRNA-Seq studies of the Huntington’s disease (HD) postmortem striatum suggest a preferential dec...

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Detalles Bibliográficos
Autores principales: Morigaki, Ryoma, Lee, Jannifer H., Yoshida, Tomoko, Wüthrich, Christian, Hu, Dan, Crittenden, Jill R., Friedman, Alexander, Kubota, Yasuo, Graybiel, Ann M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7758501/
https://www.ncbi.nlm.nih.gov/pubmed/33362481
http://dx.doi.org/10.3389/fnana.2020.608060