Cargando…

CNS macrophages differentially rely on an intronic Csf1r enhancer for their development

The central nervous system hosts parenchymal macrophages, known as microglia, and non-parenchymal macrophages, collectively termed border-associated macrophages (BAMs). Microglia, but not BAMs, were reported to be absent in mice lacking a conserved Csf1r enhancer: the fms-intronic regulatory element...

Descripción completa

Detalles Bibliográficos
Autores principales: Munro, David A. D., Bradford, Barry M., Mariani, Samanta A., Hampton, David W., Vink, Chris S., Chandran, Siddharthan, Hume, David A., Pridans, Clare, Priller, Josef
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Company of Biologists Ltd 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7758622/
https://www.ncbi.nlm.nih.gov/pubmed/33323375
http://dx.doi.org/10.1242/dev.194449