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Recruitment of BAF to the nuclear envelope couples the LINC complex to endoreplication

DNA endoreplication has been implicated as a cell strategy for cell growth and in tissue injury. Here, we demonstrate that barrier-to-autointegration factor (BAF) represses endoreplication in Drosophila myofibers. We show that BAF localization at the nuclear envelope is eliminated in flies with muta...

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Detalles Bibliográficos
Autores principales: Unnikannan, C. P., Reuveny, Adriana, Grunberg, Dvorah, Volk, Talila
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Company of Biologists Ltd 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7758627/
https://www.ncbi.nlm.nih.gov/pubmed/33168584
http://dx.doi.org/10.1242/dev.191304