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Thymosin β4 is essential for adherens junction stability and epidermal planar cell polarity

Planar cell polarity (PCP) is essential for tissue morphogenesis and homeostasis; however, the mechanisms that orchestrate the cell shape and packing dynamics required to establish PCP are poorly understood. Here, we identified a major role for the globular (G)-actin-binding protein thymosin-β4 (TMS...

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Detalles Bibliográficos
Autores principales: Padmanabhan, Krishnanand, Grobe, Hanna, Cohen, Jonathan, Soffer, Arad, Mahly, Adnan, Adir, Orit, Zaidel-Bar, Ronen, Luxenburg, Chen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Company of Biologists Ltd 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7758630/
https://www.ncbi.nlm.nih.gov/pubmed/33310787
http://dx.doi.org/10.1242/dev.193425