Cargando…

Discovery of Novel Coumarin Analogs against the α-Glucosidase Protein Target of Diabetes Mellitus: Pharmacophore-Based QSAR, Docking, and Molecular Dynamics Simulation Studies

[Image: see text] Diabetes mellitus (DM) is a chronic metabolic disease, the third killer of mankind. The finding of potent drugs against diabetes remains challenging. In the present study, coumarin derivatives with known biological activity against diabetic protein have been used to predict functio...

Descripción completa

Detalles Bibliográficos
Autores principales: Maurya, Akhilesh Kumar, Mulpuru, Viswajit, Mishra, Nidhi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2020
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7758891/
https://www.ncbi.nlm.nih.gov/pubmed/33376861
http://dx.doi.org/10.1021/acsomega.0c03871