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Indirect cholinergic activation slows down pancreatic cancer growth and tumor-associated inflammation

BACKGROUND: Nerve-cancer interactions are increasingly recognized to be of paramount importance for the emergence and progression of pancreatic cancer (PCa). Here, we investigated the role of indirect cholinergic activation on PCa progression through inhibition of acetylcholinesterase (AChE) via cli...

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Detalles Bibliográficos
Autores principales: Pfitzinger, Paulo L., Fangmann, Laura, Wang, Kun, Demir, Elke, Gürlevik, Engin, Fleischmann-Mundt, Bettina, Brooks, Jennifer, D’Haese, Jan G., Teller, Steffen, Hecker, Andreas, Jesinghaus, Moritz, Jäger, Carsten, Ren, Lei, Istvanffy, Rouzanna, Kühnel, Florian, Friess, Helmut, Ceyhan, Güralp Onur, Demir, Ihsan Ekin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7758936/
https://www.ncbi.nlm.nih.gov/pubmed/33357230
http://dx.doi.org/10.1186/s13046-020-01796-4