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Indirect cholinergic activation slows down pancreatic cancer growth and tumor-associated inflammation
BACKGROUND: Nerve-cancer interactions are increasingly recognized to be of paramount importance for the emergence and progression of pancreatic cancer (PCa). Here, we investigated the role of indirect cholinergic activation on PCa progression through inhibition of acetylcholinesterase (AChE) via cli...
Autores principales: | Pfitzinger, Paulo L., Fangmann, Laura, Wang, Kun, Demir, Elke, Gürlevik, Engin, Fleischmann-Mundt, Bettina, Brooks, Jennifer, D’Haese, Jan G., Teller, Steffen, Hecker, Andreas, Jesinghaus, Moritz, Jäger, Carsten, Ren, Lei, Istvanffy, Rouzanna, Kühnel, Florian, Friess, Helmut, Ceyhan, Güralp Onur, Demir, Ihsan Ekin |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7758936/ https://www.ncbi.nlm.nih.gov/pubmed/33357230 http://dx.doi.org/10.1186/s13046-020-01796-4 |
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