Cargando…

Enhanced Affinity for 3-Amino-Chromane-Derived σ(1) Receptor Ligands

[Image: see text] The σ(1) receptor is implicated in regulating a diverse range of physiology and is a target for developing therapies for cancer, pain management, neural degradation, and COVID-19. This report describes 36 phenethylamine-containing 3-amino-chromane ligands, which bind to σ(1) with l...

Descripción completa

Detalles Bibliográficos
Autores principales: Porter, Matthew R., Xiao, Haiyan, Maity, Sanjay, Vail, Nora, Smith, Sylvia B., Topczewski, Joseph J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2020
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7758967/
https://www.ncbi.nlm.nih.gov/pubmed/33376910
http://dx.doi.org/10.1021/acsomega.0c05117