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Preparation of a Growth Hormone Receptor/Prolactin Receptor Bispecific Antibody Antagonist Which Exhibited Anti-Cancer Activity

Prolactin receptor (PRLR) and growth hormone receptor (GHR) are closely related to the occurrence and development of breast cancer, and breast cancer cell endogenously express GHR, PRLR and GHR-PRLR heterodimer. In this case, the combined use of PRLR or GHR inhibitors may produce better anti-breast...

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Detalles Bibliográficos
Autores principales: Chen, Xin, Wu, Di, Zheng, Yan, Liu, Xingxing, Wang, Jianmeng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7759028/
https://www.ncbi.nlm.nih.gov/pubmed/33362552
http://dx.doi.org/10.3389/fphar.2020.598423