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Sevoflurane preconditioning attenuates hypoxia/reoxygenation injury of H9c2 cardiomyocytes by activation of the HIF-1/PDK-1 pathway

BACKGROUND: Sevoflurane preconditioning (SPC) can provide myocardial protective effects similar to ischemic preconditioning (IPC). However, the underlying molecular mechanism of SPC remains unclear. Studies confirm that hypoxia-inducible factor-1 (HIF-1) can transform cells from aerobic oxidation to...

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Detalles Bibliográficos
Autores principales: Hou, Tianliang, Ma, Haiping, Wang, Haixia, Chen, Chunling, Ye, Jianrong, Ahmed, Ahmed Mohamed, Zheng, Hong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: PeerJ Inc. 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7759118/
https://www.ncbi.nlm.nih.gov/pubmed/33391885
http://dx.doi.org/10.7717/peerj.10603