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A selective transmembrane recognition mechanism by a membrane-anchored ubiquitin ligase adaptor

While it is well-known that E3 ubiquitin ligases can selectively ubiquitinate membrane proteins in response to specific environmental cues, the underlying mechanisms for the selectivity are poorly understood. In particular, the role of transmembrane regions, if any, in target recognition remains an...

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Detalles Bibliográficos
Autores principales: Arines, Felichi Mae, Hamlin, Aaron Jeremy, Yang, Xi, Liu, Yun-Yu Jennifer, Li, Ming
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Rockefeller University Press 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7759299/
https://www.ncbi.nlm.nih.gov/pubmed/33351099
http://dx.doi.org/10.1083/jcb.202001116