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A selective transmembrane recognition mechanism by a membrane-anchored ubiquitin ligase adaptor
While it is well-known that E3 ubiquitin ligases can selectively ubiquitinate membrane proteins in response to specific environmental cues, the underlying mechanisms for the selectivity are poorly understood. In particular, the role of transmembrane regions, if any, in target recognition remains an...
Autores principales: | Arines, Felichi Mae, Hamlin, Aaron Jeremy, Yang, Xi, Liu, Yun-Yu Jennifer, Li, Ming |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Rockefeller University Press
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7759299/ https://www.ncbi.nlm.nih.gov/pubmed/33351099 http://dx.doi.org/10.1083/jcb.202001116 |
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