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Repurposing of renin inhibitors as SARS-COV-2 main protease inhibitors: A computational study

The COVID-19 pandemic has urged for the repurposing of existing drugs for rapid management and treatment. Renin inhibitors down regulation of ACE2, which is an essential receptor for SARS-CoV-2 infection that is responsible for COVID-19, in addition to their ability to act as protease inhibitors wer...

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Detalles Bibliográficos
Autores principales: Refaey, Rana H., El-Ashrey, Mohamed K., Nissan, Yassin M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier Inc. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7759334/
https://www.ncbi.nlm.nih.gov/pubmed/33370597
http://dx.doi.org/10.1016/j.virol.2020.12.008