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Co-movement of astral microtubules, organelles and F-actin by dynein and actomyosin forces in frog egg cytoplasm

How bulk cytoplasm generates forces to separate post-anaphase microtubule (MT) asters in Xenopus laevis and other large eggs remains unclear. Previous models proposed that dynein-based, inward organelle transport generates length-dependent pulling forces that move centrosomes and MTs outwards, while...

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Detalles Bibliográficos
Autores principales: Pelletier, James F, Field, Christine M, Fürthauer, Sebastian, Sonnett, Matthew, Mitchison, Timothy J
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7759381/
https://www.ncbi.nlm.nih.gov/pubmed/33284105
http://dx.doi.org/10.7554/eLife.60047