Selective activation of FZD7 promotes mesendodermal differentiation of human pluripotent stem cells

WNT proteins are secreted symmetry breaking signals that interact with cell surface receptors of the FZD family to regulate a multitude of developmental processes. Studying selectivity between WNTs and FZDs has been hampered by the paucity of purified WNT proteins and by their apparent non-selective...

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Detalles Bibliográficos
Autores principales: Gumber, Diana, Do, Myan, Suresh Kumar, Neya, Sonavane, Pooja R, Wu, Christina C N, Cruz, Luisjesus S, Grainger, Stephanie, Carson, Dennis, Gaasterland, Terry, Willert, Karl
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2020
Materias:
Developmental Biology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7759383/
https://www.ncbi.nlm.nih.gov/pubmed/33331818
http://dx.doi.org/10.7554/eLife.63060

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7759383/
https://www.ncbi.nlm.nih.gov/pubmed/33331818
http://dx.doi.org/10.7554/eLife.63060

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