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NLRX1 Deletion Increases Ischemia-Reperfusion Damage and Activates Glucose Metabolism in Mouse Heart

BACKGROUND: NOD-like receptors (NLR) are intracellular sensors of the innate immune system, with the NLRP3 being a pro-inflammatory member that modulates cardiac ischemia-reperfusion injury (IRI) and metabolism. No information is available on a possible role of anti-inflammatory NLRs on IRI and meta...

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Detalles Bibliográficos
Autores principales: Zhang, Hong, Xiao, Yang, Nederlof, Rianne, Bakker, Diane, Zhang, Pengbo, Girardin, Stephen E., Hollmann, Markus W., Weber, Nina C., Houten, Sander M., van Weeghel, Michel, Kibbey, Richard G., Zuurbier, Coert J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7759503/
https://www.ncbi.nlm.nih.gov/pubmed/33362773
http://dx.doi.org/10.3389/fimmu.2020.591815