Melatonin Attenuates Sepsis-Induced Acute Lung Injury Through Improvement of Epithelial Sodium Channel-Mediated Alveolar Fluid Clearance Via Activation of SIRT1/SGK1/Nedd4-2 Signaling Pathway

Acute lung injury is characterized by alveolar vascular barrier injury, and protein-rich pulmonary oedema. Alveolar fluid clearance is closely related to the prognosis of patients with acute lung injury. Melatonin has been shown to have a protective effect on multiple organ injury induced by sepsis....

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Detalles Bibliográficos
Autores principales: Li, Jing, Liu, Longfei, Zhou, Xiaojun, Lu, Xianzhou, Liu, Xianrong, Li, Guojuan, Long, Jianwu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2020
Materias:
Pharmacology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7759566/
https://www.ncbi.nlm.nih.gov/pubmed/33362546
http://dx.doi.org/10.3389/fphar.2020.590652

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7759566/
https://www.ncbi.nlm.nih.gov/pubmed/33362546
http://dx.doi.org/10.3389/fphar.2020.590652

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