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Modulation of the Mechanisms Driving Transthyretin Amyloidosis

Transthyretin (TTR) amyloidoses are systemic diseases associated with TTR aggregation and extracellular deposition in tissues as amyloid. The most frequent and severe forms of the disease are hereditary and associated with amino acid substitutions in the protein due to single point mutations in the...

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Detalles Bibliográficos
Autores principales: Bezerra, Filipa, Saraiva, Maria João, Almeida, Maria Rosário
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7759661/
https://www.ncbi.nlm.nih.gov/pubmed/33362465
http://dx.doi.org/10.3389/fnmol.2020.592644