Formulation of Orally Disintegrating Films as an Amorphous Solid Solution of a Poorly Water-Soluble Drug

The objective of the present study was to develop an orally disintegrating film (ODF) for a poorly water-soluble drug, phenytoin (PHT), using the cosolvent solubilization technique to achieve the amorphization of the drug, followed by the preparation of ODFs. Eleven formulations were prepared with d...

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Detalles Bibliográficos
Autores principales: Panraksa, Pattaraporn, Tipduangta, Pratchaya, Jantanasakulwong, Kittisak, Jantrawut, Pensak
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7759778/
https://www.ncbi.nlm.nih.gov/pubmed/33261025
http://dx.doi.org/10.3390/membranes10120376

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7759778/
https://www.ncbi.nlm.nih.gov/pubmed/33261025
http://dx.doi.org/10.3390/membranes10120376

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