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Formulation of Orally Disintegrating Films as an Amorphous Solid Solution of a Poorly Water-Soluble Drug

The objective of the present study was to develop an orally disintegrating film (ODF) for a poorly water-soluble drug, phenytoin (PHT), using the cosolvent solubilization technique to achieve the amorphization of the drug, followed by the preparation of ODFs. Eleven formulations were prepared with d...

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Detalles Bibliográficos
Autores principales:	Panraksa, Pattaraporn, Tipduangta, Pratchaya, Jantanasakulwong, Kittisak, Jantrawut, Pensak
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2020
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7759778/ https://www.ncbi.nlm.nih.gov/pubmed/33261025 http://dx.doi.org/10.3390/membranes10120376

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