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The Protective Effects of Flavonoids in Cataract Formation through the Activation of Nrf2 and the Inhibition of MMP-9

Cataracts account for over half of global blindness. Cataracts formations occur mainly due to aging and to the direct insults of oxidative stress and inflammation to the eye lens. The nuclear factor-erythroid-2-related factor 2 (Nrf2), a transcriptional factor for cell cytoprotection, is known as th...

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Detalles Bibliográficos
Autores principales: Hilliard, Aaron, Mendonca, Patricia, Russell, Tanya D., Soliman, Karam F. A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7759919/
https://www.ncbi.nlm.nih.gov/pubmed/33261005
http://dx.doi.org/10.3390/nu12123651