Unraveling the Resistance of IGF-Pathway Inhibition in Ewing Sarcoma

SIMPLE SUMMARY: The insulin-like growth factor-1 receptor (IGF1R) is a receptor commonly overexpressed and overactivated in a variety of cancers, including Ewing sarcoma, and promotes cell growth and survival. After promising results with targeting and inhibiting the receptor in vitro, multiple diff...

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Detalles Bibliográficos
Autores principales: de Groot, Stefanie, Röttgering, Bas, Gelderblom, Hans, Pijl, Hanno, Szuhai, Karoly, Kroep, Judith R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7759976/
https://www.ncbi.nlm.nih.gov/pubmed/33260481
http://dx.doi.org/10.3390/cancers12123568

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7759976/
https://www.ncbi.nlm.nih.gov/pubmed/33260481
http://dx.doi.org/10.3390/cancers12123568

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