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Coarse-Grained Simulations Suggest the Epsin N-Terminal Homology Domain Can Sense Membrane Curvature without Its Terminal Amphipathic Helix

[Image: see text] Nanoscale membrane curvature is a common feature in cell biology required for functions such as endocytosis, exocytosis and cell migration. These processes require the cytoskeleton to exert forces on the membrane to deform it. Cytosolic proteins contain specific motifs which bind t...

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Detalles Bibliográficos
Autores principales: Belessiotis-Richards, Alexis, Higgins, Stuart G., Sansom, Mark S. P., Alexander-Katz, Alfredo, Stevens, Molly M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2020
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7760104/
https://www.ncbi.nlm.nih.gov/pubmed/33300799
http://dx.doi.org/10.1021/acsnano.0c05960