RAC1B Regulation of TGFB1 Reveals an Unexpected Role of Autocrine TGFβ1 in the Suppression of Cell Motility

SIMPLE SUMMARY: Transforming growth factor (TGF)β secreted by cancer cells and acting in an autostimulatory manner has been implicated in epithelial-mesenchymal transition and cellular invasion. However, the upstream inducers/downstream effectors, or the effects on cell migration, of endogenously pr...

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Detalles Bibliográficos
Autores principales: Ungefroren, Hendrik, Otterbein, Hannah, Wellner, Ulrich F., Keck, Tobias, Lehnert, Hendrik, Marquardt, Jens-Uwe
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7760153/
https://www.ncbi.nlm.nih.gov/pubmed/33260366
http://dx.doi.org/10.3390/cancers12123570

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7760153/
https://www.ncbi.nlm.nih.gov/pubmed/33260366
http://dx.doi.org/10.3390/cancers12123570

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