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DNA Polymerases at the Eukaryotic Replication Fork Thirty Years after: Connection to Cancer

SIMPLE SUMMARY: The etiology of cancer is linked to the occurrence of mutations during the reduplication of genetic material. Mutations leading to low replication fidelity are the culprits of many hereditary and sporadic cancers. The archetype of the current model of replication fork was proposed 30...

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Detalles Bibliográficos
Autores principales: Pavlov, Youri I., Zhuk, Anna S., Stepchenkova, Elena I.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7760166/
https://www.ncbi.nlm.nih.gov/pubmed/33255191
http://dx.doi.org/10.3390/cancers12123489