Nanoparticle System Based on Amino-Dextran as a Drug Delivery Vehicle: Immune-Stimulatory CpG-Oligonucleotide Loading and Delivery

The aim of this study is to prepare and characterize an amino-dextran nanoparticle (aDNP) platform and investigate two loading strategies for unmethylated cytosine-phosphate-guanine (CpG) oligonucleotide. aDNP was prepared by desolvation of amino-dextran followed by the chemical crosslinking of amin...

Descripción completa

Detalles Bibliográficos
Autores principales: Nguyen, Hien V., Campbell, Katrin, Painter, Gavin F., Young, Sarah L., Walker, Greg F.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7760314/
https://www.ncbi.nlm.nih.gov/pubmed/33260874
http://dx.doi.org/10.3390/pharmaceutics12121150

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7760314/
https://www.ncbi.nlm.nih.gov/pubmed/33260874
http://dx.doi.org/10.3390/pharmaceutics12121150

Ejemplares similares