One Step Closer to Clinical Translation: Enhanced Tumor Targeting of [(99m)Tc]Tc-DB4 and [(111)In]In-SG4 in Mice Treated with Entresto

Background: Peptide radioligands may serve as radionuclide carriers to tumor sites overexpressing their cognate receptor for diagnostic or therapeutic purposes. Treatment of mice with the neprilysin (NEP)-inhibitor phosphoramidon was previously shown to improve the metabolic stability and tumor upta...

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Detalles Bibliográficos
Autores principales: Kanellopoulos, Panagiotis, Kaloudi, Aikaterini, Rouchota, Maritina, Loudos, George, de Jong, Marion, Krenning, Eric P., Nock, Berthold A., Maina, Theodosia
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7760338/
https://www.ncbi.nlm.nih.gov/pubmed/33256013
http://dx.doi.org/10.3390/pharmaceutics12121145

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7760338/
https://www.ncbi.nlm.nih.gov/pubmed/33256013
http://dx.doi.org/10.3390/pharmaceutics12121145

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