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Mobilization of Iron Stored in Bacterioferritin Is Required for Metabolic Homeostasis in Pseudomonas aeruginosa

Iron homeostasis offers a significant bacterial vulnerability because pathogens obtain essential iron from their mammalian hosts, but host-defenses maintain vanishingly low levels of free iron. Although pathogens have evolved mechanisms to procure host-iron, these depend on well-regulated iron homeo...

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Detalles Bibliográficos
Autores principales: Punchi Hewage, Achala N. D., Fontenot, Leo, Guidry, Jessie, Weldeghiorghis, Thomas, Mehta, Anil K., Donnarumma, Fabrizio, Rivera, Mario
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7760384/
https://www.ncbi.nlm.nih.gov/pubmed/33255203
http://dx.doi.org/10.3390/pathogens9120980