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Deep Learning for Prediction and Optimization of Fast-Flow Peptide Synthesis

[Image: see text] The chemical synthesis of polypeptides involves stepwise formation of amide bonds on an immobilized solid support. The high yields required for efficient incorporation of each individual amino acid in the growing chain are often impacted by sequence-dependent events such as aggrega...

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Detalles Bibliográficos
Autores principales: Mohapatra, Somesh, Hartrampf, Nina, Poskus, Mackenzie, Loas, Andrei, Gómez-Bombarelli, Rafael, Pentelute, Bradley L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2020
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7760468/
https://www.ncbi.nlm.nih.gov/pubmed/33376788
http://dx.doi.org/10.1021/acscentsci.0c00979