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Kidney-Targeted Cytosolic Delivery of siRNA Using a Small-Sized Mirror DNA Tetrahedron for Enhanced Potency

[Image: see text] A proper intracellular delivery method with target tissue specificity is critical to utilize the full potential of therapeutic molecules including siRNAs while minimizing their side effects. Herein, we prepare four small-sized DNA tetrahedrons (sTds) by self-assembly of different s...

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Detalles Bibliográficos
Autores principales: Thai, Hien Bao Dieu, Kim, Kyoung-Ran, Hong, Kyung Tae, Voitsitskyi, Taras, Lee, Jun-Seok, Mao, Chengde, Ahn, Dae-Ro
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2020
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7760472/
https://www.ncbi.nlm.nih.gov/pubmed/33376785
http://dx.doi.org/10.1021/acscentsci.0c00763