‘There and Back Again’—Forward Genetics and Reverse Phenotyping in Pulmonary Arterial Hypertension

Although the invention of right heart catheterisation in the 1950s enabled accurate clinical diagnosis of pulmonary arterial hypertension (PAH), it was not until 2000 when the landmark discovery of the causative role of bone morphogenetic protein receptor type II (BMPR2) mutations shed new light on...

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Detalles Bibliográficos
Autores principales: Swietlik, Emilia M., Prapa, Matina, Martin, Jennifer M., Pandya, Divya, Auckland, Kathryn, Morrell, Nicholas W., Gräf, Stefan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7760524/
https://www.ncbi.nlm.nih.gov/pubmed/33256119
http://dx.doi.org/10.3390/genes11121408

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7760524/
https://www.ncbi.nlm.nih.gov/pubmed/33256119
http://dx.doi.org/10.3390/genes11121408

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