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Nanosuspensions and Microneedles Roller as a Combined Approach to Enhance Diclofenac Topical Bioavailability

Topical application of the anti-inflammatory drug diclofenac (DCF) reduces the severity of systemic unwanted effects compared to its oral administration. A number of transdermal formulations are available on the market and routinely used in clinical and home-care settings. However, the amount of DCF...

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Detalles Bibliográficos
Autores principales: Pireddu, Rosa, Schlich, Michele, Marceddu, Salvatore, Valenti, Donatella, Pini, Elena, Fadda, Anna Maria, Lai, Francesco, Sinico, Chiara
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7760567/
https://www.ncbi.nlm.nih.gov/pubmed/33255623
http://dx.doi.org/10.3390/pharmaceutics12121140