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Nanosuspensions and Microneedles Roller as a Combined Approach to Enhance Diclofenac Topical Bioavailability
Topical application of the anti-inflammatory drug diclofenac (DCF) reduces the severity of systemic unwanted effects compared to its oral administration. A number of transdermal formulations are available on the market and routinely used in clinical and home-care settings. However, the amount of DCF...
Autores principales: | Pireddu, Rosa, Schlich, Michele, Marceddu, Salvatore, Valenti, Donatella, Pini, Elena, Fadda, Anna Maria, Lai, Francesco, Sinico, Chiara |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7760567/ https://www.ncbi.nlm.nih.gov/pubmed/33255623 http://dx.doi.org/10.3390/pharmaceutics12121140 |
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