Cargando…

Nanosuspensions and Microneedles Roller as a Combined Approach to Enhance Diclofenac Topical Bioavailability

Topical application of the anti-inflammatory drug diclofenac (DCF) reduces the severity of systemic unwanted effects compared to its oral administration. A number of transdermal formulations are available on the market and routinely used in clinical and home-care settings. However, the amount of DCF...

Descripción completa

Detalles Bibliográficos
Autores principales:	Pireddu, Rosa, Schlich, Michele, Marceddu, Salvatore, Valenti, Donatella, Pini, Elena, Fadda, Anna Maria, Lai, Francesco, Sinico, Chiara
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2020
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7760567/ https://www.ncbi.nlm.nih.gov/pubmed/33255623 http://dx.doi.org/10.3390/pharmaceutics12121140

Ejemplares similares

Nanosuspension-Based Dissolvable Microneedle Arrays to Enhance Diclofenac Skin Delivery
por: Casula, Luca, et al.
Publicado: (2023)

Needle-Free Jet Injectors and Nanosuspensions: Exploring the Potential of an Unexpected Pair
por: Schlich, Michele, et al.
Publicado: (2022)

Pulmonary Delivery of Curcumin and Beclomethasone Dipropionate in a Multicomponent Nanosuspension for the Treatment of Bronchial Asthma
por: Casula, Luca, et al.
Publicado: (2021)

Transcutol(®) P Containing SLNs for Improving 8-Methoxypsoralen Skin Delivery
por: Pitzanti, Giulia, et al.
Publicado: (2020)

Deferasirox Nanosuspension Loaded Dissolving Microneedles for Intradermal Delivery
por: Faizi, Hafsa Shahid, et al.
Publicado: (2022)

Enhancement of oral bioavailability of quercetin by metabolic inhibitory nanosuspensions compared to conventional nanosuspensions
por: Li, Haowen, et al.
Publicado: (2021)

Nanosuspension-Based Dissolving Microneedle Arrays for Intradermal Delivery of Curcumin
por: Abdelghany, Sharif, et al.
Publicado: (2019)

Design and development of topical liposomal formulations in a regulatory perspective
por: Schlich, Michele, et al.
Publicado: (2021)

Combination of Dissolving Microneedles with Nanosuspension and Co-Grinding for Transdermal Delivery of Ketoprofen
por: Ramadon, Delly, et al.
Publicado: (2023)

Development and characterization of nanosuspensions of olmesartan medoxomil for bioavailability enhancement
por: Thakkar, Hetal Paresh, et al.
Publicado: (2011)

Enhanced oral bioavailability of fluvastatin by using nanosuspensions containing cyclodextrin
por: Li, Jun, et al.
Publicado: (2018)

Unintended widespread facial autoinoculation of varicella by home microneedling roller device
por: Leatham, Hayley, et al.
Publicado: (2018)

Novel nanosuspension‐based dissolving microneedle arrays for transdermal delivery of a hydrophobic drug
por: Vora, Lalit K., et al.
Publicado: (2018)

Preparation and characterization of amorphous ezetimibe nanosuspensions intended for enhancement of oral bioavailability
por: Thadkala, Kiran, et al.
Publicado: (2014)

Enhanced bioavailability of danazol nanosuspensions by wet milling and high-pressure homogenization
por: Kanthamneni, Naveen, et al.
Publicado: (2016)

Improving Breviscapine Oral Bioavailability by Preparing Nanosuspensions, Liposomes and Phospholipid Complexes
por: Song, Zilin, et al.
Publicado: (2021)

Assessment of solid microneedle rollers to enhance transmembrane delivery of doxycycline and inhibition of MMP activity
por: Omolu, Abbie, et al.
Publicado: (2017)

Effect of Penetration Enhancer Containing Vesicles on the Percutaneous Delivery of Quercetin through New Born Pig Skin
por: Chessa, Maura, et al.
Publicado: (2011)

Development and Evaluation of Tannic Acid-Coated Nanosuspension for Enhancing Oral Bioavailability of Curcumin
por: Lee, Hyeonmin, et al.
Publicado: (2021)

Enhanced Intradermal Delivery of Nanosuspensions of Antifilariasis Drugs Using Dissolving Microneedles: A Proof of Concept Study
por: Permana, Andi Dian, et al.
Publicado: (2019)

Cefquinome Sulfate Oily Nanosuspension Designed for Improving its Bioavailability in the Treatment of Veterinary Infections
por: Mao, Yujuan, et al.
Publicado: (2022)

Chitosan grafted methoxy poly(ethylene glycol)-poly(ε-caprolactone) nanosuspension for ocular delivery of hydrophobic diclofenac
por: Shi, Shuai, et al.
Publicado: (2015)

Comparison of Downstream Processing of Nanocrystalline Solid Dispersion and Nanosuspension of Diclofenac Acid to Develop Solid Oral Dosage Form
por: Jadhav, Sanika, et al.
Publicado: (2020)

Importance of the formulation in the skin delivery of topical diclofenac: not all topical diclofenac formulations are the same
por: Pradal, Julie, et al.
Publicado: (2019)

SLN as a topical delivery system for Artemisia arborescens essential oil: In vitro antiviral activity and skin permeation study
por: Lai, Francesco, et al.
Publicado: (2007)

Topical Diclofenac-Induced Hepatotoxicity
por: Delungahawatta, Thilini, et al.
Publicado: (2023)

In vitro dissolution and bioavailability study of furosemide nanosuspension prepared using design of experiment (DoE)
por: Shariare, Mohammad H., et al.
Publicado: (2019)

Enhanced oral bioavailability of magnolol via mixed micelles and nanosuspensions based on Soluplus(®)-Poloxamer 188
por: Li, Guoyuan, et al.
Publicado: (2020)

Efficient delivery of nucleic acid molecules into skin by combined use of microneedle roller and flexible interdigitated electroporation array
por: Huang, Dong, et al.
Publicado: (2018)

Formulation of Aceclofenac Tablets Using Nanosuspension as Granulating Agent: An Attempt to Enhance Dissolution Rate and Oral Bioavailability
por: Rahim, Haroon, et al.
Publicado: (2020)

Diclofenac topical solution compared with oral diclofenac: a pooled safety analysis
por: Roth, Sanford H, et al.
Publicado: (2011)

Silver sulfadiazine nanosuspension-loaded thermosensitive hydrogel as a topical antibacterial agent
por: Liu, Xiaoya, et al.
Publicado: (2018)

Custom fractional factorial designs to develop atorvastatin self-nanoemulsifying and nanosuspension delivery systems – enhancement of oral bioavailability
por: Hashem, Fahima M, et al.
Publicado: (2015)

Fabrication and characterization of glimepiride nanosuspension by ultrasonication-assisted precipitation for improvement of oral bioavailability and in vitro α-glucosidase inhibition
por: Rahim, Haroon, et al.
Publicado: (2019)

Development of Nanosuspension of Artemisia absinthium Extract as Novel Drug Delivery System to Enhance Its Bioavailability and Hepatoprotective Potential
por: Jahan, Nazish, et al.
Publicado: (2023)

Severe photosensitivity reaction induced by topical diclofenac
por: Akat, Pramod B.
Publicado: (2013)

Fabrication and Characterization of Glimepiride Nanosuspension by Ultrasonication-Assisted Precipitation for Improvement of Oral Bioavailability and in vitro α-Glucosidase Inhibition [Corrigendum]
Publicado: (2020)

Transformation of Meloxicam Containing Nanosuspension into Surfactant-Free Solid Compositions to Increase the Product Stability and Drug Bioavailability for Rapid Analgesia
por: Bartos, Csaba, et al.
Publicado: (2019)

Fabrication and Characterization of Glimepiride Nanosuspension by Ultrasonication-Assisted Precipitation for Improvement of Oral Bioavailability and in vitro α-Glucosidase Inhibition [Retraction]
Publicado: (2022)

The Roller Bandage
Publicado: (1883)

Cannot write session to /tmp/vufind_sessions/sess_tb4ld21kvagn2no5t6gcoji48p