Screening of Human CYP1A2 and CYP3A4 Inhibitors from Seaweed In Silico and In Vitro

Phenolic compounds and carotenoids are potential inhibitors of cytochrome P450s. Sixteen known compounds, phenolic compounds and carotenoids from seaweed were examined for potential inhibitory capacity against CYP1A2 and CYP3A4 in silico and in vitro. Morin, quercetin, and fucoxanthin inhibited the...

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Detalles Bibliográficos
Autores principales: Yim, Sung-Kun, Kim, Kian, Chun, SangHo, Oh, TaeHawn, Jung, WooHuk, Jung, KyooJin, Yun, Chul-Ho
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7760626/
https://www.ncbi.nlm.nih.gov/pubmed/33260381
http://dx.doi.org/10.3390/md18120603

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7760626/
https://www.ncbi.nlm.nih.gov/pubmed/33260381
http://dx.doi.org/10.3390/md18120603

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