Structural Basis of Zika Virus Specific Neutralization in Subsequent Flavivirus Infections

Zika virus (ZIKV), a mosquito-borne human flavivirus that causes microcephaly and other neurological disorders, has been a recent focus for the development of flavivirus vaccines and therapeutics. We report here a 4.0 Å resolution structure of the mature ZIKV in complex with ADI-30056, a ZIKV-specif...

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Detalles Bibliográficos
Autores principales: Sevvana, Madhumati, Rogers, Thomas F., Miller, Andrew S., Long, Feng, Klose, Thomas, Beutler, Nathan, Lai, Yen-Chung, Parren, Mara, Walker, Laura M., Buda, Geeta, Burton, Dennis R., Rossmann, Michael G., Kuhn, Richard J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7760643/
https://www.ncbi.nlm.nih.gov/pubmed/33255202
http://dx.doi.org/10.3390/v12121346

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7760643/
https://www.ncbi.nlm.nih.gov/pubmed/33255202
http://dx.doi.org/10.3390/v12121346

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