Cargando…

Structural Basis of Zika Virus Specific Neutralization in Subsequent Flavivirus Infections

Zika virus (ZIKV), a mosquito-borne human flavivirus that causes microcephaly and other neurological disorders, has been a recent focus for the development of flavivirus vaccines and therapeutics. We report here a 4.0 Å resolution structure of the mature ZIKV in complex with ADI-30056, a ZIKV-specif...

Descripción completa

Detalles Bibliográficos
Autores principales:	Sevvana, Madhumati, Rogers, Thomas F., Miller, Andrew S., Long, Feng, Klose, Thomas, Beutler, Nathan, Lai, Yen-Chung, Parren, Mara, Walker, Laura M., Buda, Geeta, Burton, Dennis R., Rossmann, Michael G., Kuhn, Richard J.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2020
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7760643/ https://www.ncbi.nlm.nih.gov/pubmed/33255202 http://dx.doi.org/10.3390/v12121346

Ejemplares similares

Principles of Virus Structure
por: Sevvana, Madhumati, et al.
Publicado: (2021)

Structure-guided paradigm shifts in flavivirus assembly and maturation mechanisms
por: Nicholls, Conrrad M.R., et al.
Publicado: (2020)

Structure of the immature Zika virus at 9 Å resolution
por: Prasad, Vidya Mangala, et al.
Publicado: (2017)

New Anti-Flavivirus Fusion Loop Human Antibodies with Zika Virus-Neutralizing Potential
por: França, Renato Kaylan Alves de Oliveira, et al.
Publicado: (2022)

Reporter Virus Neutralization Test Evaluation for Dengue and Zika Virus Diagnosis in Flavivirus Endemic Area
por: Nunes, Jannyce G. C., et al.
Publicado: (2021)

Seroprevalence of Flavivirus Neutralizing Antibodies in Thailand by High-Throughput Neutralization Assay: Endemic Circulation of Zika Virus before 2012
por: Yamanaka, Atsushi, et al.
Publicado: (2021)

Cryo-EM Structures of Eastern Equine Encephalitis Virus Reveal Mechanisms of Virus Disassembly and Antibody Neutralization
por: Hasan, S. Saif, et al.
Publicado: (2018)

Zika, Flavivirus and Malaria Antibody Cocirculation in Nigeria
por: Mac, Peter Asaga, et al.
Publicado: (2023)

The mysterious Zika virus: Adding to the tropical flavivirus mayhem
por: Mishra, B, et al.
Publicado: (2016)

Zika and Flavivirus Shell Disorder: Virulence and Fetal Morbidity
por: Goh, Gerard Kian-Meng, et al.
Publicado: (2019)

Nucleic Acid Vaccine Platform for DENGUE and ZIKA Flaviviruses
por: Taslem Mourosi, Jarin, et al.
Publicado: (2022)

Capturing a Flavivirus Pre-Fusion Intermediate
por: Kaufmann, Bärbel, et al.
Publicado: (2009)

Cryo-EM structures of alphavirus conformational intermediates in low pH–triggered prefusion states
por: Chen, Chun-Liang, et al.
Publicado: (2022)

The epitope arrangement on flavivirus particles contributes to Mab C10’s extraordinary neutralization breadth across Zika and dengue viruses
por: Sharma, Arvind, et al.
Publicado: (2021)

Impact of prior flavivirus immunity on Zika virus infection in rhesus macaques
por: McCracken, Michael K., et al.
Publicado: (2017)

Thermodynamic Mechanism for the Evasion of Antibody Neutralization in Flaviviruses
por: Maillard, Rodrigo A., et al.
Publicado: (2014)

Zika Virus Is Not Uniquely Stable at Physiological Temperatures Compared to Other Flaviviruses
por: Goo, Leslie, et al.
Publicado: (2016)

Evaluation of serological test of Zika in an endemic area of flavivirus in the Colombian Caribbean
por: Arrieta, German, et al.
Publicado: (2019)

Capsid protein structure in Zika virus reveals the flavivirus assembly process
por: Tan, Ter Yong, et al.
Publicado: (2020)

Non-merohedral twinning: from minerals to proteins
por: Sevvana, Madhumati, et al.
Publicado: (2019)

Nonstructural Proteins Are Preferential Positive Selection Targets in Zika Virus and Related Flaviviruses
por: Sironi, Manuela, et al.
Publicado: (2016)

Sexual transmission of Zika virus and other flaviviruses: A living systematic review
por: Counotte, Michel Jacques, et al.
Publicado: (2018)

Update on non-vector transmission of dengue: relevant studies with Zika and other flaviviruses
por: Chen, Lin H., et al.
Publicado: (2016)

Label-Free Electrochemical Biosensors for the Determination of Flaviviruses: Dengue, Zika, and Japanese Encephalitis
por: Khristunova, Ekaterina, et al.
Publicado: (2020)

Zika RNA and Flavivirus-Like Antigens in the Sperm Cells of Symptomatic and Asymptomatic Subjects
por: Vanegas, Hernan, et al.
Publicado: (2021)

A human antibody against Zika virus crosslinks the E protein to prevent infection
por: Hasan, S. Saif, et al.
Publicado: (2017)

Structural basis for STAT2 suppression by flavivirus NS5
por: Wang, Boxiao, et al.
Publicado: (2020)

Restriction of Zika virus infection and transmission in Aedes aegypti mediated by an insect-specific flavivirus
por: Romo, Hannah, et al.
Publicado: (2018)

Zika Virus and Sexual Transmission: A New Route of Transmission for Mosquito-borne Flaviviruses 
por: Hastings, Andrew K., et al.
Publicado: (2017)

A Tale of Two Viruses: Does Heterologous Flavivirus Immunity Enhance Zika Disease?
por: Sariol, Carlos A., et al.
Publicado: (2018)

Impact of flavivirus vaccine-induced immunity on primary Zika virus antibody response in humans
por: Malafa, Stefan, et al.
Publicado: (2020)

Pathogenesis of flavivirus encephalitis
por: Chambers, Thomas J, et al.
Publicado: (2003)

First Complete Genome Sequence of Zika Virus (Flaviviridae, Flavivirus) from an Autochthonous Transmission in Brazil
por: Cunha, Mariana Sequetin, et al.
Publicado: (2016)

T cell immunity to Zika virus targets immunodominant epitopes that show cross-reactivity with other Flaviviruses
por: Reynolds, C. J., et al.
Publicado: (2018)

Previous dengue or Zika virus exposure can drive to infection enhancement or neutralisation of other flaviviruses
por: Oliveira, Renato AS, et al.
Publicado: (2019)

Lipid Metabolism as a Source of Druggable Targets for Antiviral Discovery against Zika and Other Flaviviruses
por: Martín-Acebes, Miguel A., et al.
Publicado: (2019)

Musashi binding elements in Zika and related Flavivirus 3′UTRs: A comparative study in silico
por: Schneider, Adriano de Bernardi, et al.
Publicado: (2019)

Identification of diagnostic peptide regions that distinguish Zika virus from related mosquito-borne Flaviviruses
por: Lee, Alexandra J., et al.
Publicado: (2017)

Antibody Immunity to Zika Virus among Young Children in a Flavivirus-Endemic Area in Nicaragua
por: Zepeda, Omar, et al.
Publicado: (2023)

A Simple and High-Throughput ELISA-Based Neutralization Assay for the Determination of Anti-Flavivirus Neutralizing Antibodies
por: Balingit, Jean Claude, et al.
Publicado: (2020)

Cannot write session to /tmp/vufind_sessions/sess_fjcvqd612k00urlm8u5vrug61u