Metabolic Drug Response Phenotyping in Colorectal Cancer Organoids by LC-QTOF-MS

As metabolic rewiring is crucial for cancer cell proliferation, metabolic phenotyping of patient-derived organoids is desirable to identify drug-induced changes and trace metabolic vulnerabilities of tumor subtypes. We established a novel protocol for metabolomic and lipidomic profiling of colorecta...

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Detalles Bibliográficos
Autores principales: Neef, Sylvia K., Janssen, Nicole, Winter, Stefan, Wallisch, Svenja K., Hofmann, Ute, Dahlke, Marc H., Schwab, Matthias, Mürdter, Thomas E., Haag, Mathias
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7760698/
https://www.ncbi.nlm.nih.gov/pubmed/33271860
http://dx.doi.org/10.3390/metabo10120494

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7760698/
https://www.ncbi.nlm.nih.gov/pubmed/33271860
http://dx.doi.org/10.3390/metabo10120494

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