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Metabolic Drug Response Phenotyping in Colorectal Cancer Organoids by LC-QTOF-MS

As metabolic rewiring is crucial for cancer cell proliferation, metabolic phenotyping of patient-derived organoids is desirable to identify drug-induced changes and trace metabolic vulnerabilities of tumor subtypes. We established a novel protocol for metabolomic and lipidomic profiling of colorecta...

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Detalles Bibliográficos
Autores principales:	Neef, Sylvia K., Janssen, Nicole, Winter, Stefan, Wallisch, Svenja K., Hofmann, Ute, Dahlke, Marc H., Schwab, Matthias, Mürdter, Thomas E., Haag, Mathias
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2020
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7760698/ https://www.ncbi.nlm.nih.gov/pubmed/33271860 http://dx.doi.org/10.3390/metabo10120494

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