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Modeling the Molecular Impact of SARS-CoV-2 Infection on the Renin-Angiotensin System

SARS-CoV-2 infection is mediated by the binding of its spike protein to the angiotensin-converting enzyme 2 (ACE2), which plays a pivotal role in the renin-angiotensin system (RAS). The study of RAS dysregulation due to SARS-CoV-2 infection is fundamentally important for a better understanding of th...

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Detalles Bibliográficos
Autores principales: Pucci, Fabrizio, Bogaerts, Philippe, Rooman, Marianne
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7760740/
https://www.ncbi.nlm.nih.gov/pubmed/33265982
http://dx.doi.org/10.3390/v12121367