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Optimization of Liposomes for Antigen Targeting to Splenic CD169(+) Macrophages

Despite promising progress in cancer vaccination, therapeutic effectiveness is often insufficient. Cancer vaccine effectiveness could be enhanced by targeting vaccine antigens to antigen-presenting cells, thereby increasing T-cell activation. CD169-expressing splenic macrophages efficiently capture...

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Detalles Bibliográficos
Autores principales: Nijen Twilhaar, Maarten K., Czentner, Lucas, Grabowska, Joanna, Affandi, Alsya J., Lau, Chun Yin Jerry, Olesek, Katarzyna, Kalay, Hakan, van Nostrum, Cornelus F., van Kooyk, Yvette, Storm, Gert, den Haan, Joke M.M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7760819/
https://www.ncbi.nlm.nih.gov/pubmed/33255564
http://dx.doi.org/10.3390/pharmaceutics12121138