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Optimization of Liposomes for Antigen Targeting to Splenic CD169(+) Macrophages
Despite promising progress in cancer vaccination, therapeutic effectiveness is often insufficient. Cancer vaccine effectiveness could be enhanced by targeting vaccine antigens to antigen-presenting cells, thereby increasing T-cell activation. CD169-expressing splenic macrophages efficiently capture...
Autores principales: | Nijen Twilhaar, Maarten K., Czentner, Lucas, Grabowska, Joanna, Affandi, Alsya J., Lau, Chun Yin Jerry, Olesek, Katarzyna, Kalay, Hakan, van Nostrum, Cornelus F., van Kooyk, Yvette, Storm, Gert, den Haan, Joke M.M. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7760819/ https://www.ncbi.nlm.nih.gov/pubmed/33255564 http://dx.doi.org/10.3390/pharmaceutics12121138 |
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